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(2)
By Target- Apoptosis
- Autophagy(1)
- NF-κB(1)
- Phospholipase(1)
- p38 MAPK(1)
- Others(1)
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By Target By ResearchField- Metabolism(1)
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Results for "
malabaricone c
" in TargetMol Product Catalog.- Inhibitors & Agonists2
- Natural Products1
- ML-20T211068ML-20, an analog of Malabaricone C, functions as both an autophagy inhibitor and a radiosensitizer. It suppresses cell proliferation and induces apoptosis (cell death). ML-20 also causes DNA double-strand breaks, loss of mitochondrial membrane potential (MMP), and lysosomal membrane permeabilization (LMP). Due to LMP, it triggers endoplasmic reticulum stress while concurrently inhibiting autophagic flux.
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