mal peg5 mal

Mal-PEG5-mal is a PEG-based linker for PROTACs, joining two essential ligands crucial for PROTAC molecule formation and enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Mal-PEG5-Boc (Mal-PEG5-COOtBu) is a PEG-based PROTAC linker. Mal-PEG5-Boc can be used in the synthesis of PROTACs.

Mal-PEG5-acid is a PEG-based linker for PROTACs, joining two essential ligands essential for forming PROTAC molecules. This linker facilitates selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Mal-PEG5-NHS ester, an alkyl/ether and PEG-based PROTAC linker, is utilized for the synthesis of PROTACs.

Mal-PEG5-PFP ester is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules. This linker facilitates selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Bis-Mal-PEG5 is a PEG-based linker for PROTACs, joining two essential ligands necessary for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Mal-amido-PEG10-C2-NHS ester is a noncleavable ADC linker with a maleimide group and an NHS ester, used as a labeling agent for primary amines (-NH2) in proteins, amine-modified oligonucleotides, and other amine-containing molecules [1][2].

Mal-amido-PEG5-acid is a PROTAC linker categorized under the PEG class, used for the synthesis of PROTAC molecules.

m-PEG5-amino-Mal, a PROTAC linker from the PEG category, is utilized in the synthesis of PROTAC molecules.

Mal-CO-PEG5-NHS ester is a 5-unit PEG-based, non-cleavable ADC linker utilized in the fabrication of antibody-drug conjugates (ADCs).

Mal-PEG5-C2-NH2 hydrochloride is a polyethylene glycol (PEG)-based linker used in the synthesis of proteolysis targeting chimeras (PROTACs).

Mal-PEG5-amine is a PEG linker that contains a maleimide group and an amine group. The hydrophilic PEG spacer enhances its solubility in aqueous media. The amine group can react with carboxylic acids, activated NHS esters, and carbonyl groups (ketones, aldehydes), while the maleimide group can form covalent bonds with thiol groups, allowing biomolecules to connect via thiol linkage.

Mal-PEG5-NH-Boc is a PEG linker incorporating a maleimide group and a Boc-protected amine. The hydrophilic PEG spacer enhances its solubility in aqueous media. The protected amine group can be deprotected under acidic conditions. The maleimide group reacts with thiol groups to form a covalent bond.