macrophylla

Phyllodulcin, an orally active sweetener discovered in Hydrangea macrophylla var. thunbergii, functions as a non-selective phosphodiesterase inhibitor that mitigates allergic reactions by suppressing the activation of lymphocytes. Additionally, it combats obesity through the regulation of leptin levels, genes associated with fat browning, and the hypothalamic BDNF-TrkB signaling pathway.

(-)-Phyllocladene is a natural product from Callicarpa macrophylla.

Apocynol A is a natural product from Hydrangea macrophylla.

6alpha-Hydroxynidorellol is a natural product from Callicarpa macrophylla.

Secaubryenol is a 3,4-secocycloartane triterpenes isolated from Coussarea macrophylla.

Corynoxine hydrochloride, a tetracyclic oxindole alkaloid extracted from the hooks of Uncaria macrophylla, functions as a natural autophagy enhancer, facilitating the removal of alpha-synuclein by activating the Akt mTOR pathway [1].

Corynoxine is a tetracyclic oxindole alkaloid isolated from Uncaria macrophylla. It is an autophagy enhancer that promotes α-synuclein clearance through the Akt mTOR pathway.

Hemiphroside A is a natural product from Hydrangea macrophylla.

Erythrocentauric acid is a natural product from Gentiana macrophylla.

(+)-Licarin A (Compound 7), an octanoid neolignan, is derived from the leaves of Ocotea macrophylla Kunth [1].