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m-344

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
M344
MS 344, Histone Deacetylase Inhibitor III
T2157251456-60-7
M344 (Histone Deacetylase Inhibitor III) is a potent HDAC inhibitor with IC50 of 100 nM and able to induce cell differentiation.
  • $47
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YM-344031
T88324671204-98-1
YM-344031 is an orally administered antagonist targeting CCR3. It effectively inhibits the binding of Eotaxin-1 and RANTES to CCR3, with IC50 values of 3.0 and 16.3 nM, respectively. YM-344031 also suppresses ligand-induced increases in intracellular Ca [2+] levels and chemotaxis, alters eosinophil morphology induced by eotaxin-1 in macaque blood, and prevents allergic skin reactions in a mouse allergy model.
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10-14 weeks
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