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By Target- Apoptosis
- Caspase(1)
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Results for "
lucidenic acid b
" in TargetMol Product Catalog- Inhibitors & Agonists1
- Natural Products1
Lucidenic acid B
Lucidenicacid B
TN188095311-95-8
Lucidenic acid B (Lucidenicacid B), a natural compound extracted from Ganoderma lucidum, induces activation of caspase-9 and caspase-3 and cleavage of PARP, which can induce apoptosis in human leukemia cells through mitochondrial mediation. Lucidenic acid B inhibits PMA-induced invasion of human hepatocellular carcinoma cells by inactivating the MAPK ERK signaling pathway and decreasing the binding activity of NF-kappaB and AP-1. Lucidenic acid B had no effect on cell cycle and necrotic cells.
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