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Results for "
lmi070
" in TargetMol Product Catalog- Inhibitors & Agonists3
Branaplam
NVS-SM1, LMI 070
T46411562338-42-4
Branaplam (LMI 070) is a highly potent, selective and orally active small molecule SMN2 splicing modulator.
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Branaplam mesylate (1562338-42-4 free base)
LMI070,Branaplam mesylate,LMI 070,LMI-070
T26893
Branaplam is a highly potent, selective and orally active SMN2 splicing modulator. Branaplam increases the amount of functional SMN protein produced by the SMN2 gene through modifying its splicing.
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Branaplam hydrochloride
T623811562338-39-9
Branaplam (LMI070; NVS-SM1) hydrochloride is a selective, orally active SMN2 splicing modulator that acts on SMN (EC50: 20 nM) and inhibits hERG (IC50: 6.3 μM). In a mouse model of severe spinal muscular atrophy (SMA), Branaplam hydrochloride increased full-length SMN protein and improved survival.
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