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Results for "
leq-506
" in TargetMol Product Catalog- Inhibitors & Agonists4
LEQ-506
T715201057677-92-5
LEQ506, also known as NPV-LEQ506, is an orally bioavailable small-molecule Smoothened (Smo) antagonist with potential antineoplastic activity. Smoothened antagonist LEQ506 selectively binds to the Hedgehog (Hh)-ligand cell surface receptor Smo, which may result in the suppression of the Hh signaling pathway, thereby inhibiting tumor cell growth.
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LEQ-506 HCl (1204975-42-7 free base)
NPVLEQ 506, LEQ-506 HCl, LEQ-506 dihychloride, LEQ-506, LEQ506, LEQ 506
T24400
LEQ506 is an orally bioavailable small-molecule Smoothened antagonist. It also has a potential antineoplastic activity.
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Zidovudine diphosphate
T71518106060-89-3
Zidovudine diphosphate is an antiretroviral medication used to prevent and treat HIV AIDS. It is of the nucleoside analog reverse-transcriptase inhibitor (NRTI) class. Zidovudine inhibits the enzyme (reverse transcriptase) that HIV uses to synthesize DNA, thus preventing viral DNA from forming.
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LEQ506
NVP-LEQ506
T118381204975-42-7In house
LEQ506 is a Smo inhibitor with IC50s of 2 nM and 4 nM for hSmo and mSmo, respectively.
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