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Results for "

lcl-161

" in TargetMol Product Catalog.
  • Inhibitors & Agonists
    2
    TargetMol | All_Pathways
  • PROTAC Products
    1
    TargetMol | PROTAC
  • LCL161
    T20801005342-46-0
    LCL161 is a SMAC mimetic, an IAP antagonist with oral activity that inhibits XIAP (IC50=35 nM) in HEK293 cells and also inhibits cIAP1 (IC50=0.4 nM) in MDA-MB-231 cells. LCL161 has potential antitumor activity.
    • $63
    In Stock
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    TargetMol | Citations Cited
  • SNIPER(BRD)-1
    T169052095244-54-3
    SNIPER(BRD)-1 is a chemical compound composed of a derivative of the IAP antagonist LCL-161 and the BET inhibitor (+)-JQ-1, linked together. It promotes the degradation of BRD4 through the ubiquitin-proteasome pathway and effectively degrades cIAP1, cIAP2, and XIAP with IC50 values of 6.8 nM, 17 nM, and 49nM, respectively[1].
    • $2,570
    3-6 months
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