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Results for "
lau0901
" in TargetMol Product Catalog.- Inhibitors & Agonists2
- SetipafantLAU-0901, BN-50727T16874132418-35-0Setipafant is an antagonist of the platelet-activating factor.
- $1,970
SizeQTY - LAU-0901T83777727358-25-0LAU-0901, a platelet-activating factor (PAF) receptor antagonist, demonstrates efficacy in reducing infarct volume and enhancing neurological function in rats subjected to middle cerebral artery occlusion (MCAO)-induced cerebral ischemia, at doses of 30, 60, and 90 mg/kg. Furthermore, it diminishes microglial infiltration while promoting astrocytic and neuronal survival in the same model. Additionally, at a dose of 30 mg/kg, LAU-0901, either alone or combined with atorvastatin, shows a capability to inhibit tumor growth in a U87MG glioblastoma mouse orthotopic tumor model.
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