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jak-1-in-8

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  • Inhibitors & Agonists
    2
    TargetMol | All_Pathways
JAK1-IN-8
JAK1-IN-8
T358991973485-18-5
JAK1-IN-8, a specific inhibitor of Janus kinase 1 (JAK1, IC50<500 nM).
  • $39
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JAK-IN-25
Methyl 6-(1-(4-methoxybenzyl)-1H-pyrazol-4-yl)-4-oxo-4,5-dihydropyrazolo[1,5-a]pyrazine-2-carboxylate
T781752127110-22-7
JAK-IN-25 is a potent JAK inhibitor with IC50 values of 6 nM for TYK2, 21 nM for JAK1, 8 nM for JAK2, and 1051 nM for JAK3. JAK-IN-25 inhibits human whole blood IL-12 (HEB IL-12) with an IC50 of 28 nM, demonstrating its potential value in cancer research.
  • $71
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