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By Target- Wnt/beta-catenin
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By Target By ResearchField- Cancer(2)
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Results for "
iwr 1
" in TargetMol Product Catalog.- Inhibitors & Agonists2
- IWR-1IWR-1-endo, endo-IWR 1T26511127442-82-3IWR-1 (IWR-1-endo) is a tankyrase inhibitor that targets the Wnt/β-catenin pathway, with an IC₅₀ of 180 nM. IWR-1 contributes to the activation of TCF/LEF and the expression of downstream targets of the Wnt/β-catenin pathway. IWR-1 promotes β-catenin phosphorylation by enhancing the stability of the Axin-mediated disassembly complex. IWR-1 can be used in research on diseases such as cancer and psoriasis.
- $50
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Cited - exo-IWR-1exo-IWR 1T227751127442-87-8exo-IWR-1 (exo-IWR 1) is an inactive stereoisomer of Endo-IWR-1,and is a negative control of IWR-1. IWR-1 is a tankyrase inhibitor which inhibits Wnt/β-catenin signaling pathway.
- $34
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