itraconazole

Itraconazole (R51211) is a triazole antifungal agent that inhibits cytochrome P-450-dependent enzymes necessary for ERGOSTEROL synthesis.

Hydroxy Itraconazole (R63373) is a triazole compound with antifungal activity for the study of malignant tumors.

Itraconazole-d3 is a deuterated compound of Itraconazole.

Hydroxy Itraconazole D8 is the deuterium-labeled Hydroxy Itraconazole. Hydroxy Itraconazole is an active metabolite of Itraconazole, which is a triazole antifungal agent.

Keto-itraconazole is a metabolite of Itraconazole.

Itraconazole-d9 is the deuterated form of Itraconazole. Itraconazole (R51211) is a triazole antifungal agent with potent oral activity as a Hedgehog signaling pathway antagonist, exhibiting an IC50 of approximately 800 nM. It effectively inhibits lanosterol 14α-demethylase (Cytochrome P450), thus preventing the conversion of lanosterol to ergosterol. Additionally, Itraconazole exhibits anti-cancer and anti-angiogenic properties and acts as an oxysterol-binding protein (OSBP) inhibitor.

Itraconazole-d5 is a deuterated compound of Itraconazole. Itraconazole has a CAS number of 84625-61-6. Itraconazole is a triazole antifungal agent that inhibits cytochrome P-450-dependent enzymes required for ERGOSTEROL synthesis.

Itraconazole (Standard) is a reference standard for research and analysis in studies involving Itraconazole. Itraconazole (R51211) belongs to the triazole group of natural products and is an antifungal agent with oral activity. Itraconazole is a Hedgehog signaling pathway antagonist, an oxysterol-binding protein (OSBP) inhibitor, and an inhibitor of cytochrome P-450-dependent enzymes.

Hydroxy Itraconazole (Standard) is a reference standard for research and analysis in studies involving Hydroxy Itraconazole. Hydroxy Itraconazole (R63373) is a triazole compound with antifungal activity for the study of malignant tumors.

5-LOX inhibitor (1-(sec-Butyl)-4-(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)-1H-1,2,4-triazol-5(4H)-one) is one of the impurities of itraconazole, a selective LOX-5 inhibitor.