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By Target- Isocitrate Dehydrogenase (IDH)
- Dehydrogenase(1)
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Results for "
idh-1 inhibitor 2
" in TargetMol Product Catalog- Inhibitors & Agonists3
IDH1 Inhibitor 2
T116112244895-42-7
IDH1 Inhibitor 2 (compound 13) is a potent IDH1 inhibitor through direct covalent modification of His315, with an IC50 of 110 nM.
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Mutant IDH1-IN-2
T121281429176-69-1In house
Mutant IDH1-IN-2 is an inhibitor of mutant Isocitrate dehydrogenase (IDH) proteins, with an IC50 of 16.6 nM in fluorescence biochemical assay and an IC50 of <22 nM in LS-MS biochemical assay.
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Vorasidenib
PVM MA, AG-881
T73071644545-52-7
Vorasidenib (PVM MA) is an inhibitor of mutant isocitrate dehydrogenase (IDH; IC50s = 31.9 and 31.7 nM for IDH1R132H and IDH2R140Q, respectively)
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