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Results for "
i-bet151
" in TargetMol Product Catalog- Inhibitors & Agonists3
I-BET151
Cited
GSK1210151A
T21201300031-49-5
I-BET151 (GSK1210151A) (GSK1210151A) is a specific BET inhibitor for BRD2/3/4 (IC50: 0.5/0.25/0.79 μM, in cell-free assays).
- $41
Size
QTY
CitedI-BET151 dihydrochloride
I-BET 151 hydrochloride
T228451883545-47-8
I-BET 151 dihydrochloride is a BET bromodomain inhibitor that prevents BET from recruiting to chromatin.
- $1,150
Size
QTY
DW34
T2107822758171-54-7
DW34 is an orally bioactive pan-BRD4-D1-biased inhibitor that also exhibits BRD4-D2 activity. It demonstrates a low nanomolar inhibitory effect comparable to I-BET151 (EC50 value of 0.16 μM), with an EC50 value of 0.14 μM. DW34 significantly alleviates lipopolysaccharide (LPS)-induced liver inflammation and acetaminophen (APAP)-induced toxicity by reducing chemokine expression and cell necrosis.
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