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By Target- PAFR
- Platelet aggregation(1)
- iGluR(1)
- Others(1)
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Results for "
hypoxic-ischemic
" in TargetMol Product Catalog.- Inhibitors & Agonists3
- Recombinant Protein1
- RocepafantLAU-8080, LAU8080, LAU 8080, BN-50730, BN50730, BN 50730T28607132579-32-9In houseRocepafant (LAU8080) is a platelet-activating factor (PAF) antagonist that attenuates hypoxic-ischemic brain damage in neonatal rats.Rocepafant inhibits tumor necrosis factor-Afa-mediated cytotoxicity in mouse L929 tumor cells.
- $46
SizeQTY - NitromemantineYQW-036, NMI-6979, NitroSynapsinT214187765890-91-3Nitromemantine (NitroSynapsin) is a nitrate ester derivative of Memantine and acts as a bifunctional NMDAR antagonist. It demonstrates significant efficacy in rodent models of cerebral infarction through a dual mechanism of open channel blockade and NO/redox modulation of receptors. Under hypoxic conditions, Nitromemantine specifically targets ischemic neurons, enhancing its activity. It inhibits NMDA-induced currents with an IC50 of 2.4 μM and is utilized in the study of ischemic stroke.
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