hyp 1

HyP-1 is a probe for photoacoustic imaging of hypoxia.

H-Gly-Pro-Hyp-OH is a potent and orally available anti-photoaging collagen peptide that attenuates inflammation and reduces MMP-1 and MMP-3 levels; attenuates H2O2-induced aging of dermal fibroblasts; restores cortisol-mediated inhibition of type I collagen and GR activation and (TGF)-β signaling signaling, among other things; and improves the hydration of human skin, elasticity and anti-wrinkle properties.

DEALA-Hyp-YIPD, an HIF-1α peptide inhibitor, impedes the VHL HIF-1α interaction with an half-maximal inhibitory concentration (IC50) of 0.91 μM and a dissociation constant (Kd) of 180 nM [1].