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  • P2X Receptor
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hp2x7 receptor

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  • Inhibitors & Agonists
    2
    TargetMol | Inhibitors_Agonists
JNJ-54175446
JNJ-5446
T156221627902-21-9In house
JNJ-54175446 (JNJ-5446) is a CNS-permeable and selective P2X7 receptor antagonist that attenuates the release of IL-1β/IL-18 from microglia, and may be used in the study of depression.
  • $293
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P2X7 receptor antagonist-6
T2119571114621-31-6
P2X7 receptorantagonist-6 (Compound 2g) is a negative allosteric antagonist of the P2X7 receptor, which shows an IC50 of 1.31 μM against hP2X7. This compound is applicable in the study of cancer, neurodegenerative diseases, inflammation, and infectious diseases.
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10-14 weeks
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