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hn5

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
egfr/erbb-2/erbb-4 inhibitor-2
EGFR ErbB2 Inhibitor
T21954179248-61-4
EGFR ErbB-2 ErbB-4 inhibitor-2 (EGFR ErbB2 Inhibitor) is a cell-permeable compound that inhibits EGFR and c-ErbB2 with IC50 values of 20 nM and 79 nM, respectively.
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(Z)-RG-13022
(Z)-Tyrphostin RG13022
T84525149286-90-8
(Z)-RG-13022 is a tyrosine kinase (TK) inhibitor that preferentially inhibits the TK activity of the EGF receptor, restricting the EGF-stimulated growth of cultured cells. It demonstrates an IC50 of 11 μM for DNA synthesis in HN5 cells, showcasing thrice the potency of its isomer, (E)-RG-13022 (IC50 = 38 μM). This compound is applied in breast cancer cell research [1] [2].
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8-10 weeks
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