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(5)
By Target- Hedgehog/Smoothened
- Acyltransferase(2)
- Others(3)
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Search Result
Results for "
hhat
" in TargetMol Product Catalog- Inhibitors & Agonists5
RU-SKI 43
RUSKI 43
T127971043797-53-0In house
RU-SKI 43 is a potent and selective hedgehog acyltransferase (Hhat) inhibitor with an IC50 of 850 nM. It exhibits anticancer activity and is a potential treatment for lung adenocarcinomas. RU-SKI 43 reduces Gli-1 activation through smoothening-independent non-canonical signaling and inhibits Akt and mTOR pathway activity.
- $118
Size
QTY
RU-SKI 43 Hydrochloride
RU-SKI43 Hydrochloride
T12797L1782573-67-4
RU-SKI 43 Hydrochloride is a potent and selective inhibitor of Hedgehog acyltransferase (Hhat), with an IC50 value of 850 nM. RU-SKI 43 Hydrochloride has been reported to possess anticancer activity, making it a useful compound for investigating Hedgehog signaling in tumor biology.
- $73
Size
QTY
IMP-1575
T2090443026255-85-3
IMP-1575 is a highly effective inhibitor of hedgehog acyltransferase (HHAT), with an IC50 of 0.75 μM when inhibiting purified HHAT. IMP-1575 has potential applications in cancer research.
Inquiry
RUSKI-201
RU-SKI-201
T344511458031-48-5
RUSKI-201 is the first selective Hedgehog acyltransferase (Hhat) chemical probe in cells.
- $1,520
Size
QTY
RUSKI-201 dihydrochloride
T623882320262-09-5
RUSKI-201 dihydrochloride is a potent and specific inhibitor of Hedgehog acyltransferase (Hhat) (IC50: 0.20 μM). It blocks Hh signaling in Shh-overexpressing cells and inhibits Hh palmitoylation. RUSKI-201 dihydrochloride is a promising Hhat chemical probe for studying Hhat catalytic function.
- $218
Size
QTY
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