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(5)
By Target- Hedgehog/Smoothened
- Acyltransferase(2)
- Others(3)
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By Target By ResearchField- Cancer(3)
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Results for "
hhat
" in TargetMol Product Catalog.- Inhibitors & Agonists5
- RU-SKI 43RUSKI 43T127971043797-53-0In houseRU-SKI 43 is a potent and selective hedgehog acyltransferase (Hhat) inhibitor with an IC50 of 850 nM. It exhibits anticancer activity and is a potential treatment for lung adenocarcinomas. RU-SKI 43 reduces Gli-1 activation through smoothening-independent non-canonical signaling and inhibits Akt and mTOR pathway activity.
- $45
SizeQTY - RU-SKI 43 HydrochlorideRU-SKI43 HydrochlorideT12797L1782573-67-4RU-SKI 43 Hydrochloride is a potent and selective inhibitor of Hedgehog acyltransferase (Hhat), with an IC50 value of 850 nM. RU-SKI 43 Hydrochloride has been reported to possess anticancer activity, making it a useful compound for investigating Hedgehog signaling in tumor biology.
- $69
SizeQTY - IMP-1575T2090443026255-85-3IMP-1575 is a highly effective inhibitor of hedgehog acyltransferase (HHAT), with an IC50 of 0.75 μM when inhibiting purified HHAT. IMP-1575 has potential applications in cancer research.
- Inquiry Price
SizeQTY - RUSKI-201RU-SKI-201T344511458031-48-5RUSKI-201 is the first selective Hedgehog acyltransferase (Hhat) chemical probe in cells.
- $1,520
SizeQTY - RUSKI-201 dihydrochlorideT623882320262-09-5RUSKI-201 dihydrochloride is a potent and specific inhibitor of Hedgehog acyltransferase (Hhat) (IC50: 0.20 μM). It blocks Hh signaling in Shh-overexpressing cells and inhibits Hh palmitoylation. RUSKI-201 dihydrochloride is a promising Hhat chemical probe for studying Hhat catalytic function.
- $218
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