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By Target By ResearchField- Cancer(2)
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Results for "
herboxidiene
" in TargetMol Product Catalog- Inhibitors & Agonists2
- Natural Products1
Herboxidiene
GEX1A
T36749142861-00-5
Herboxidiene (GEX1A) is a plant-toxic polyketide compound isolated from Streptomyces ATCC 49982, with herbicidal, cholesterol-lowering, and anticancer activities. It exhibits anti-angiogenic activity by downregulating vascular endothelial growth factor receptor-2 (VEGFR-2) and hypoxia-inducible factor-1α (HIF-1α).
- $740
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18-Deoxyherboxidiene
T622671200128-66-0
18-Deoxyherboxidiene (RQN-18690A) is a potent inhibitor of angiogenesis that selectively acts on SF3b, a subcomplex of the U2 small nuclear ribonucleoprotein (snRNP) in the spliceosome. It inhibits migration and tube formation in human umbilical vein endothelial cells (HUVEC) without significant cytotoxicity and has potential for cancer research.
- $5,049
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