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hellebrigenin

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  • Inhibitors & Agonists
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Hellebrigenin
TN1728465-90-7
Hellebrigenin, as a selective inhibitor of MAPK signaling pathways (ERK, p38, JNK) and XIAP, effectively suppresses Akt expression and phosphorylation. This compound activates endogenous apoptosis pathways (including mitochondrial membrane potential disruption, Caspase family activation, and PARP cleavage) while modulating apoptosis-related protein expression. Hellebrigenin also induces DNA double-strand breaks to activate the ATM pathway, inhibiting tumor cell proliferation and clonogenesis, primarily applied in research of oral squamous cell carcinoma and liver cancer.
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Hellebrigenin-3-O-?-glucoside
T129680
Hellebrigenin-3-O-?-glucoside is a useful organic compound for research related to life sciences and the catalog number is T129680.
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