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(1)
By Target- Apoptosis
- Prostaglandin Receptor(1)
- TNF(1)
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Results for "
hdp receptor
" in TargetMol Product Catalog- Inhibitors & Agonists2
- Peptide Products1
AGN 210676
Simenepag
T14146910562-15-1
AGN 210676 is a selective agonist of prostaglandin EP2(EC50 : 5 nM).
- $1,820
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QTY
RP-832c
TP39442375823-45-1
RP-832c is a synthetic analog of a host defense peptide (HDP) that targets the mannose receptor CD206 on M2-polarized macrophages with a Kd of 3.5 μM. Upon binding to CD206, RP-832c induces significant conformational changes in the receptor, activating signaling pathways that lead to rapid apoptosis of CD206-positive M2 macrophages and their repolarization to the M1 phenotype. Treatment with RP-832c significantly reduces CD206 gene expression in M2 macrophages and temporarily increases the expression of the M1 macrophage marker TNF-α. RP-832c is applicable for research on T-cell lymphomas (CTCL) and idiopathic pulmonary fibrosis (IPF).
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