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hbv nucleocapsid assembly

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
BA-53038B
T104462306195-65-1In house
BA-53038B is an HBV core protein allosteric modulator (CpAM), binding to the HAP pocket and modulating HBV capsid assembly in a distinct manner (EC50: 3.32 μM).
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6-8 weeks
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GLP-26
T114092133017-36-2
GLP-26 disrupts the encapsidation of pre-genomic RNA, causes nucleocapsid disassembly and reduces cccDNA pools. GLP-26 is a HBV capsid assembly modulators (CAM), inhibits HBV DNA replication in Hep AD38 system (IC50=3 nM), and reduces cccDNA by >90% at 1
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