hbp

Hydrocortisone buteprate is a medium-potent, non-halogenated double-ester derivative of hydrocortisone that has researches indicate highly favorable benefit-to-risk ratio in inflammatory dermatological disorders.

FR054 is an inhibitor of the Hexosamine Biosynthetic Pathway (HBP) enzyme PGM3, with a remarkable anti-breast cancer effect, inducing a dramatic decrease in cell proliferation and survival in various breast cancer cells.

DHBP (Benzoresorcinol) is an WalKR TCS activator. It works via targeting walk and selectively promoting the lysostaphin-induced lysis activity of the Newman wild-type strain.

DHBP dibromide (1,1'-DI-N-HEPTYL-4,4'-BIPYRIDINIUM DIBRO) is calcium release and a muscle relaxant inhibitor.

HBPC-GSH, a derivative of glutathione, functions as an inhibitor for the glyoxalase system, specifically inhibiting cGloI and cGloII with IC50 values of 0.6μM and 1.6μM, respectively. This compound is utilized in antimalarial research [1].

Thioether-cyclized helix B peptide (CHBP) enhances metabolic stability and exerts renoprotective effects by promoting autophagy through the inhibition of mTOR C1 and activation of mTOR C2 [1].

Thioether-cyclized helix B peptide, CHBP (TFA), is the trifluoroacetic (TFA) salt of CHBP, enhancing metabolic stability and exhibiting renoprotective effects by promoting autophagy through inhibition of mTOR C1 and activation of mTOR C2 [1].

DHBP (Standard) is the standard substance of DHBP, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. DHBP (Benzoresorcinol) is an WalKR TCS activator. It works via targeting walk and selectively promoting the lysostaphin-induced lysis activity of the Newman wild-type strain.

GHGVYGHGVYGHGPYGHGPYGHGLYW (DgHBP-2) is a 26-amino-acid consensus peptide derived from histidine-rich beak protein-2 (DgHBP-2) and can be used to fabricate a glucose-responsive insulin delivery system [1].

HBpep-SA acetate is a cell membrane-permeable peptide aggregate that undergoes phase separation and forms stable droplets in acidic environments with pH below 6.5, enabling efficient delivery of biomolecules (such as therapeutic peptides and enzymes) and serving as a carrier for mRNA-based vaccines.

HBpep(RPY)-SP is a variant of the polypeptide HBpep-SP. This compound interacts with lipid bilayers and has demonstrated exceptional transfection efficiency in challenging-to-transfect cells, such as primary and immune cells. HBpep(RPY)-SP is useful for research in protein, gene, and immune cell therapies.

HBpep(RPY)-SP acetate is a modified HBpep-SP peptide that forms co-condensate microdroplets by liquid-liquid phase separation and directly crosses the cell membrane, independently of the classical endocytosis pathway, thus enabling intracellular delivery and efficient release of biomolecules (e.g., peptides, proteins, and mRNAs), and it can also be used for transfection.

HBpep(RPY)-SP TFA is an optimized phase-separating peptide capable of liquid-liquid phase separation to form conjugated microdroplets over a wide pH range (6.5-9.0). It is highly efficient in the delivery of a wide range of biomolecules and can be used in difficult-to-transfect cells.

Selinexor (KPT-330) is a small molecule inhibitor of CRM1 with selective and oral activity. Selinexor blocks the cell cycle, induces apoptosis, and has antitumor activity for the treatment of multiple myeloma.

UDP-GlcNAc Disodium Salt (UDP-α-D-N-Acetylglucosamine Disodium Salt) is a nucleotide sugar synthesized from glucose through the hexosamine biosynthetic pathway (HBP).

(6R)-FR054 is an inhibitor of the Hexosamine Biosynthetic Pathway (HBP) enzyme PGM3, with a remarkable anti-breast cancer effect.