h 7 dihydrochloride

Protein kinase inhibitor H-7 dihydrochloride(H-7 dihydrochloride) is a potent protein kinase C (PKC) inhibitor. Protein kinase inhibitor H-7 dihydrochloride (100 μM) significantly inhibits TPA (skin tumor promoter, 12-O-tetradecanoylphorbol-13-acetate) and phospholipase C-induced ODC (ornithine decarboxylase) inhibited PMA-induced promiscuity cell lysis activity.

Iso-H7 dihydrochloride is a less potent inhibitor of phosphokinase C than H-7.

L-Arginine 7-amido-4-methylcoumarin dihydrochloride is a specialized fluorescent substrate with potential for detecting cathepsin H activity. It provides a high-sensitivity fluorescent signal for biological research and holds significant application in enzyme activity assays.