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By Target- Histone Demethylase
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Results for "
gsk-j-4 hydrochloride
" in TargetMol Product Catalog.- Inhibitors & Agonists1
- GSK-J4 HydrochlorideGSK J4 HCl (1373423-53-0 free base), GSK J4 HClT43831797983-09-5GSK-J4 Hydrochloride (GSK J4 HCl) is a cell permeable, potent and selective histone demethylase(JMJD3 )inhibitor. is an ethyl ester derivative of the GSK-J1 with an IC50 value greater than 50 μM in vitro.
- $34
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- GSK-J4
GSK J4T31001373423-53-0In houseGSK-J4 (GSK J4 HCl) is a cell permeable prodrug of GSK-J1, a dual inhibitor of the H3K27me3/me2 demethylases JMJD3/KDM6B and UTX/KDM6A (IC50=8.6/6.6 μM). GSK-J4 induces endoplasmic reticulum stress-related apoptosis.- $51
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