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gossypol

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  • Inhibitors & Agonists
    9
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(S)-Gossypol acetic acid
(S)-(+)-Gossypol acetic acid
T139801189561-66-7
(S)-Gossypol acetic acid ((S)-(+)-Gossypol acetic acid) is a conformational isomer of Gossypol that acts as a BH3 mimic capable of binding Bcl-xL and Bcl-2 proteins, with the potential to induce apoptosis and inhibit cell growth.
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7-10 days
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Gossypol
Pogosin, BL 193, NSC 56817
T6518303-45-7
Gossypol (BL 193) Acetate is a polyphenolic aldehyde that permeates cells and acts as an inhibitor for several dehydrogenase enzymes.
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Gossypol (acetic acid)
Pogosin, Gossypol acetic acid, AT101, (±)-Gossypol-acetic acid
T273012542-36-8
Gossypol acetic acid (AT101), a polyphenolic compound isolated from cottonseeds, binds with Bcl-2, Bcl-xL, Mcl-1, and does not inhibit BIR3 domain and BID.
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(R)-(-)-Gossypol acetic acid
AT101 acetic acid, AT-101 (acetic acid), (R)-Gossypol acetic acid, (-)-Gossypol acetic acid
T6396866541-93-7
(R)-(-)-Gossypol acetic acid (AT101 acetate), the R-(-) enantiomer of Gossypol acetic acid, binds with Bcl-2, Bcl-xL, and Mcl-1 with Ki values of 0.32 μM, 0.48 μM, and 0.18 μM, respectively; it does not inhibit the BIR3 domain or BID. [Phase 2]
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Hemigossypol
T3205640817-07-0
Hemigossypol is a precursor of gossypol biosynthesis.
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