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By Target- DYRK
- GSK-3(1)
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- Thyroid hormone receptor(THR)
- 5-HT Receptor
- Adenosine Receptor
- Adiponectin receptor
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- Apelin receptor
- Arrestin
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- cAMP
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- CRFR
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Results for "
gnf-4877
" in TargetMol Product Catalog.- Inhibitors & Agonists1
- GNF4877T114472041073-22-5In houseGNF4877 is a small molecule inhibitor, a potent dual-specificity kinase inhibitor targeting DYRK1A (IC50=6 nM) and GSK3β (IC50=16 nM). This compound promotes β-cell proliferation by blocking NFATc nuclear export (EC50=0.66 μM for mouse R7T1 cells) and is primarily used for research on β-cell regeneration related to diabetes.
- $56
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