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(1)
By Target- Apoptosis
- DNA/RNA Synthesis(1)
- Others(2)
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Results for "
genomic stability
" in TargetMol Product Catalog- Inhibitors & Agonists2
- Compound Libraries1
- Recombinant Protein5
IDE275, IDE 275, GSK 4418959
T2040893064599-36-3
GSK4418959 (IDE275) is a non-covalent, reversible, selective, and orally active inhibitor of the Werner syndrome helicase (WRN helicase). GSK4418959 inhibits both ATPase and DNA unwinding activities of WRN helicase in an ATP-competitive manner. GSK4418959 is a valuable chemical tool for the study of microsatellite instability-high (MSI-H) cancers, where WRN helicase plays an essential role in maintaining genomic stability.
- $413
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QTY
PF-3837
T2000612772910-13-9
PF-3837 is an inhibitor of the Mps1 kinase, with a Ki value of 0.33 nM and an IC50 value of 5.5 nM. It disrupts cell cycle checkpoints by inhibiting the catalytic activity of Mps1, thereby reducing genomic stability and leading to cancer cell apoptosis (Apoptosis). PF-3837 is utilized in the study of breast cancer.
- $2,870
Size
QTY
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