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By Target- Caspase
- DUB(1)
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Results for "
gdc-2394
" in TargetMol Product Catalog.- Inhibitors & Agonists3
- GDC-2394T697452238822-07-4GDC-2394, an orally active, selective NLRP3 inhibitor, also targets IL-1β, exhibiting inhibitory concentrations (IC50s) of 0.4 μM (human IL-1β) and 0.1 μM (mouse IL-1β). It effectively hampers NLRP3-induced caspase-1 activity while not affecting NLRC4-dependent inflammasome activation.
- $1,250
SizeQTY - GDC-2394 sodium saltGDC2394 sodium saltT69745L2238822-08-5GDC-2394 sodium salt is an orally active selective NLRP3 inhibitor that concurrently inhibits IL-1β with IC50 values of 0.4 μM (human) and 0.1 μM (mouse). This compound specifically inhibits NLRP3-induced caspase-1 activity without affecting NLRC4-dependent inflammasome activation.
- $195
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