gastroduodenal ulcer

Rebamipide (OPC12759) is a quinolinone derivative with anti-ulcer and anti-inflammatory activities. Rebamipide induces cyclooxygenase 2 (COX2) synthesis which results in an increase in endogenous prostaglandin synthesis in the gastric mucosa. This agent also inhibits H. pylori-induced production of tumor necrosis factor (TNF) alpha and subsequent inflammation of the gastric mucosa. In addition, rebamipide scavenges oxygen-derived free radicals that potentially cause mucosal injury, and stimulates prostaglandin EP4 receptor gene expression followed by mucous secretion, thereby enhancing the gastric mucosal defense.

Cyclic somatostatin (SRIF-14) is a cyclic tetradecapeptide that regulates various endocrine and nervous system functions.

Vonoprazan (TAK-438 (free base)) is an orally active potassium-competitive acid blocker.Vonoprazan can be used for the treatment of gastroduodenal ulcer and reflux esophagitis

Vonoprazan-D3 is a deuterated compound of Vonoprazan. Vonoprazan (T8388) has a CAS number of 881681-00-1. Vonoprazan (T8388) is an orally active potassium-competitive acid blocker.Vonoprazan can be used for the treatment of gastroduodenal ulcer and reflux esophagitis

Vonoprazan-D4 is a deuterated compound of Vonoprazan. Vonoprazan (T8388) has a CAS number of 881681-00-1. Vonoprazan (T8388) is an orally active potassium-competitive acid blocker.Vonoprazan can be used for the treatment of gastroduodenal ulcer and reflux esophagitis