gambogic acid

Gambogic Acid (Guttic Acid) ( EC50=0.78-1.64 uM) activates caspases. Gambogic Acid competitively suppresses Bcl-XL, Bcl-2, Bcl-W, Bcl-B, Bfl-1 and Mcl-1. The IC50s of Gambogic Acid for Bcl-XL, Bcl-2, Bcl-W, Bcl-B, Bfl-1 and Mcl-1 are 1.47, 1.21, 2.02, 0.66, 1.06 and 0.79 uM, respectively.

Gambogic acid A is a useful organic compound for research related to life sciences and the catalog number is T125707.

Gambogic acid B, isolated from Garcinia hanburyi resin, exhibits cytotoxic effects on A549, HCT116, and MDA-MB-231 cell lines with respective IC50 values of 1.60 µM, 6.88 µM, and 0.87 µM [1].

Neogambogic acid, an active ingredient in garcinia, can inhibit the growth of some solid tumors [resulting in an anticancer effect], and may be responsible for the inhibition of proliferation of human breast cancer cell line MCF-7 cells.

30-Hydroxygambogic acid is a useful organic compound for research related to life sciences and the catalog number is T124009.

10alpha-Hydroxyepigambogic acid is a useful organic compound for research related to life sciences and the catalog number is T126303.

9R-10alpha-Hydroxyepigambogic acid is a useful organic compound for research related to life sciences and the catalog number is T126415.

Epigambogic acid is a small molecule compound from Garcinia Cambogia with anti-tumor, antitussive, expectorant and anti-inflammatory activities.

"S-30-Hydroxygambogic acid, a polyprenylated xanthone epimer isolated from the gamboges of Garcinia hanburyi, exhibits cytotoxicity against Human Leukemia K562 cell lines with IC50 values of 4.49 μM for K562/R and 3.61 μM for K562/S. This compound is utilized in cancer research [1]."

R-30-Hydroxygambogic acid, a polyprenylated xanthone epimer isolated from the gamboge of Garcinia hanburyi, exhibits cytotoxicity against human leukemia K562 cell lines, with IC50 values of 2.89 μM for the resistant strain (K562/R) and 1.27 μM for the sensitive strain (K562/S). This compound is utilized in cancer research [1].

8,8a-Dihydro-8-hydroxygambogic acid, a natural compound extracted from the resin of Garcinia hanburyi, exhibits anticancer activity [1].

10α-Hydroxyepigambogic acid, extracted from Garcinia hanburyi, is utilized in tumor research [1].

Isogambogic acid shows cytotoxic activiity against KB and drug-resistant KB-V1 cell lines.

Isogambogic acid(C2-S) is a natural product that can be used in related research in the field of life sciences. Its product number is TN8796.