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Results for "

galectin9

" in TargetMol Product Catalog
  • Recombinant Protein
    3
    TargetMol | Recombinant_Protein
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Galectin-9/LGALS9 Protein, Human, Recombinant (GST & His)
Tumor antigen HOM-HD-21, LGALS9, Galectin-9, Gal-9, Ecalectin
TMPH-01364
Expression system: E. coli
Length: 1-323, Full length of Isoform 2
Activity: Not Tested
  • Inquiry Price
20 days
Size
QTY
Buffer-exchangeable
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Galectin-9 Protein, Human, Recombinant (His)
Tumor Antigen HOM-HD-21, LGALS9, Galectin-9, Gal-9, Ecalectin
TMPJ-01455
Expression system: HEK293 Cells
Length: 1-323, Full Length of Isoform 2
Activity: Not Tested
  • Inquiry Price
7-10 days
Size
QTY
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TIM-3/KIM-3/HAVCR2 Protein, Cynomolgus, Recombinant (His)
Tim-3, TIM3, T cell immunoglobulin and mucin domain3, HAVCR2
TMPJ-00189
T cell immunoglobulin and mucin domain 3 is a member of the TIM family of immune regulating molecules. Mature cynomolgus TIM3 consists of a 182 amino acid (aa)extracellular domain (ECD), a 21 aa transmembrane segment, and a 78 aa cytoplasmic tail. TIM3 is up-regulated on several populations of activated myeloid cells (macrophage, monocyte, dendritic cell, microglia, mast cell) and T cells (Th1, CD8+, NK, Treg). Its binding to Galectin9 induces a range of immunosuppressive functions which enhance immune tolerance and inhibit anti-tumor immunity. TIM3 ligation attenuates CD8+ and Th1 cell responses and promotes the activity of Treg and myeloid derived suppressor cells. TIM3 interactions with Galectin-9 can trigger immune stimulatory effects, such as the coactivation of NK cell cytotoxicity.
  • Inquiry Price
7-10 days
Size
QTY
SPR-compatible buffer