fumonisin b1

Fumonisin B1 (Fumonisin-B1) is a mycotoxin produced by Fusarium oxysporum that is widely present in crops, contaminating them and posing a significant food safety hazard.Fumonisin B1 is structurally a sphingosine and sphingomyelin analog, and inhibits the biosynthesis of complex sphingolipids through the inhibition of ceramidic synthases.

Hydrolyzed Fumonisin B1 is the backbone and the main hydrolysis product of the mycotoxin fumonisin B1 (FB1), can weakly inhibit ceramide synthase.

Fumonisin B1-13C34 is an isotopically labeled derivative of Fumonisin B1 (T15356), containing 13C. Fumonisin B1, produced by the fungus Fusarium moniliforme, is a potent inhibitor of sphingosine N-acyltransferase (ceramide synthase), interfering with de novo sphingolipid biosynthesis. It is the most prevalent and toxic fumonisin.

Torvoside C (Torvoside K) is a compound found in Solanum torvum with antifungal properties. It exhibits a zone of inhibition (ZOI) and minimum inhibitory concentration (MIC) range of 33.4-87.4% and 31.25-250 μg/mL, respectively, against tested fungi such as Alternaria brassicicola, Alternaria geophila, and Aspergillus flavus. Additionally, Torvoside C inhibits the production of mycotoxins aflatoxin B1 and fumonisin B1 in a dose-dependent manner, particularly in A. flavus and F. verticillioides. This compound is applicable in antifungal infection research.