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ft671

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  • Inhibitors & Agonists
    3
    TargetMol | Inhibitors_Agonists
FT671
T12621L1959551-26-8
FT671 is a non-covalent and selective inhibitor of USP7 (IC50: 52 nM) It also binds to the USP7 catalytic domain (Kd: 65 nM).
  • $2,120
8-10 weeks
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TargetMol | Citations Cited
(R)-FT671
T126211959551-27-9
(R)-FT671 is the R-isomer of FT671, a potent, non-covalent, and selective inhibitor of USP7 with an IC50 of 52 nM.
  • $2,120
8-10 weeks
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YCH2823
T209573
YCH2823 is an inhibitor of USP7 (IC50= 49.6 nM; Kd= 0.117 μM) and demonstrates significant efficacy in suppressing both wild-type TP53 tumors and mutated tumors. It is approximately 5 times more potent than FT671, induces apoptosis, and exhibits a synergistic effect with mTOR inhibitors.
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