exenatide

Exenatide (Extendin-4) is a glucagon-like protein-1 (GLP-1) receptor agonist.

Exendin-4 (Exenatide) is a glucagon-like peptide-1 receptor (GLP-1) agonist (IC50: 3.22 nM). Exenatide is a 39 amino acid peptide. Compared to GLP-1, exenatide has a longer half-life of 2.4 hours.

Exendin-4 acetate is a 39 amino acid peptide.Exendin-4 acetate is a long-acting GLP-1 receptor agonist(IC50 = 3.22 nM).

(Asp28)-Exenatide is a degradation product of exenatide and can be used as a GLP-1R agonist [1].

Acetyl-Exenatide, an acetylated derivative of Exenatide, mirrors insulin's functionality and is utilized in type 2 diabetes research. It promotes Th17 differentiation, inhibits Tregs differentiation, and downregulates PI3K/Akt/FoxO1 phosphorylation [1].

Exenatide acetate is a polypeptide hormone composed of 39 amino acids. As a glucagon-like peptide-1 (GLP-1) receptor agonist with an IC50 of 3.22 nM, it is indicated for the treatment of insulinoma and type 2 diabetes. Exendin acetate promotes migration, sprouting, and nitric oxide (NO) production in human umbilical vein endothelial cells (HUVECs) in vitro. It exhibits cytotoxicity towards MCF-7 cells and provides protective effects against ischaemic injury in a mouse hindlimb model.