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ercc1-xpf

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  • Inhibitors & Agonists
    3
    TargetMol | Inhibitors_Agonists
ERCC1-XPF-IN-2
T609041808986-37-9
ERCC1-XPF-IN-2 is active in nucleotide excision repair, cisplatin enhancement and γH2AX assays. ERCC1-XPF-IN-2 is a potent inhibitor of ERCC1-XPF endonuclease with an IC 50 value of 0.6 μM [1].
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6-8 weeks
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ERCC1-XPF-IN-1
T634642411584-25-1
ERCC1-XPF-IN-1 is a potent, high-affinity inhibitor of ERCC1-XPF (IC50: 0.49 μM), that inhibits the removal of CPDs, reduces the toxicity of cyclophosphamide to colorectal cancer cells, enhances the cytotoxic effects of UV radiation, and impedes DNA repair.
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6-8 weeks
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NSC16168
NSC 16168
T163516837-93-0
NSC16168 is a selective ERCC1-XPF inhibitor that inhibits DNA repair and potentiates the antitumor activity of cisplatin.
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6-8 weeks
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