epothilone d

Epothilone D is a natural polyketide compound isolated from the myxobacterium Sorangium cellulosum that binds to tubulin and inhibits microtubule disassembly, thereby blocking mitosis, cellular proliferation, and cell motility, Epothilone D is extensively utilized in cancer research to study microtubule dynamics, mitotic arrest, and cytoskeleton-targeted anticancer mechanisms.

Epothilone D1, a naturally derived isolate, exhibits cytotoxic effects on mouse fibroblasts.

cis-9,10-Dehydroepothilone D (KOS-1584) is an epoxide derivative with antiproliferative properties and activity in tubulin polymerization. This compound is useful in the study of lung cancer, colon cancer, prostate cancer, and breast cancer.

CB-892 is a novel inhibitor of hiv-1 gene expression

Epothilone F is a derivative or analogue of Epothilone D. Epothilone F is also an active metabolite of Epothilone D. In molecule of Epothilone F, a hydroxymethyl group is on the thiazole ring. Like taxanes, Epothilone F prevents cancer cells from dividing