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englerin a

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    3
    TargetMol | All_Pathways
  • Natural Products
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    TargetMol | Natural_Products
Englerin A
(-)-Englerin A
T384841094250-15-3
Englerin A, a TRPC4 and TRPC5 channel agonist, is a compound from the East African plant Phyllanthus engleri with analgesic, anti-inflammatory, and anticancer activities that induces necrosis in human renal cancer cells.
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TargetMol | Citations Cited
(-)-Englerin B
T126423
(-)-Englerin B is a natural product that can be used as a reference standard.
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Pico145
HC-608
T165321628287-16-0
Pico145 (HC-608) is a remarkable inhibitor of TRPC1/4/5 channels, specifically inhibiting ( )-englerin A-activated TRPC4/TRPC5 channels with IC50s of 0.349 and 1.3 nM in cells, while showing no effect on TRPC3, TRPC6, TRPV1, TRPV4, TRPA1, TRPM2, or TRPM8.
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