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elafibranor

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    4
    TargetMol | Inhibitors_Agonists
Elafibranor
GFT505
T4408923978-27-2
Elafibranor (GFT505) is an agonist of the peroxisome proliferator-activated receptor-α (PPAR-α) and peroxisome proliferator-activated receptor-δ (PPAR-δ) with EC50 values of 45 and 175 nM, respectively.
  • $30
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TargetMol | Inhibitor Sale
(E/Z)-Elafibranor
(E Z)-GFT505
T8699824932-88-9
(E Z)-Elafibranor ((E Z)-GFT505) is a PPARα δ agonist with EC50s of 45 and 175 nM, respectively.
  • $50
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TargetMol | Inhibitor Sale
R112
T3185575474-82-7
R112 is an ATP-competitive inhibitor of Syk kinase. Ki=6 nM,IC50=226 nM.
  • $33
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Anti-NASH agent 1
T794542409685-41-0
Anti-NASH Agent 1 (Compound 3d), derived from Elafibranor, serves as a strong PPAR-α δ agonist aimed at treating nonalcoholic steatohepatitis (NASH). At dosages of 3-10 mg kg over four weeks, this compound ameliorates hyperlipidemia, liver fat degeneration, and inflammation in a methionine-choline deficiency (MCD)-induced NASH mouse model, exhibiting minimal hepatotoxicity while providing substantial hepatic protection [1].
  • $1,520
6-8 weeks
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