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By Tag By Expression System- E. coli(1)
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Results for "
egr-1
" in TargetMol Product Catalog- Inhibitors & Agonists4
- Natural Products2
- Recombinant Protein1
Comparezinc finger protein 225, Zif268, NGFI-A, nerve growth factor-induced protein A, EGR-1, Early growth response protein 1
TMPJ-00883
EGR-1 belongs to the EGR family of C2H2-type zinc finger proteins. It is a nuclear protein and functions as a transcriptional regulator. EGR-1 recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'(EGR-site).The products of target genes it activates are required for differentiation and mitogenesis. Studies suggest this is a tumor suppressor gene. EGR-1 has a distinct pattern of expression in the brain, and its induction has been shown to be associated with neuronal activity. Several studies suggest it has a role in neuronal plasticity. EGR-1 has also been found to regulate the expression of synaptobrevin II (a protein important for synaptic exocytosis).
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