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(2)
By Target- Stearoyl-CoA Desaturase (SCD)
- TLR(2)
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By Target By ResearchField- Inflammation(2)
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Results for "
e 6446
" in TargetMol Product Catalog.- Inhibitors & Agonists2
- E6446 dihydrochlorideT40681345675-25-3E6446 dihydrochloride is a novel synthetic antagonist for nucleic acid-sensing TLRs; potently suppressed DNA stimulation of HEK:TLR9 cells with IC50 of 10 nM.
- $84
SizeQTY - E6446T42061219925-73-1E6446 inhibits Toll-like receptor (TLR)7 and 9 signaling. E6446 works in a variety of human and mouse cell types and inhibits DNA-TLR9 interaction in vitro. When administered to mice, this compound suppress responses to challenge doses of cytidine-phosphate-guanidine (CpG)-containing DNA, which stimulates TLR9.
- $84
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