dopet

Hydroxytyrosol (2-(3,4-Di-hydroxyphenyl)-ethanol) is an active ingredient extracted from the olive. It is one of the most efficient and secure antioxidants and can be used in the cardiovascular drugs.

Mesdopetam (IRL790), a dopamine D3 receptor antagonist with a Ki of 90 nM and an IC50 of 9.8 μM for the human recombinant D3 receptor, exhibits psychomotor stabilizing properties and is used in the study of motor and psychiatric complications associated with Parkinson's disease.

Mesdopetam hemitartrate (IRL790 hemitartrate) is an antagonist of dopamine D3 receptor (Ki=90 nM; IC50=9.8 μM for human recombinant D3 receptor). It has psychomotor stabilizing properties.

DOPAL is an aldehyde product of the oxidative deamination of dopamine by monoamine oxidase.[1] It can be further oxidized to 3,4-dihydroxyphenylacetic acid (DOPAC) by aldehyde dehydrogenase (ALDH) and, to a lesser extent reduced to 3,4-dihydroxyphenyl ethanol (DOPET). DOPAL is toxic to neurons.[2],[3] It can also oligomerize and precipitate α-synuclein, an event associated with Parkinson's disease.[2] Mice lacking cytosolic and mitochondrial forms of ALDH display increased levels of DOPAL as well as neurodegeneration and motor dysfunction characteristic of Parkinson's disease.[4]

Hydroxytyrosol-D5 is the deuterated form of Hydroxytyrosol. Hydroxytyrosol (T3412) (DOPET) is a phenolic compound derived from olive trees and their leaves, known for its antioxidant, anti-atherosclerotic, antithrombotic, antibacterial, anti-inflammatory, and antitumor properties.

Hydroxytyrosol-D4 is the deuterated form of Hydroxytyrosol. Hydroxytyrosol (T3412) (DOPET) is a phenolic compound extracted from the olive tree and its leaves, known for its antioxidant, anti-atherosclerotic, antithrombotic, antibacterial, anti-inflammatory, and antitumor properties.