dmg peg 2000

DMG-PEG 2000 (DMG-PEG2000) can be used for the preparation of lipid nanoparticles for the in vivo delivery of plasmid DNA via oral administration, enhancing the mucosal permeability and delivery efficiency of the nanoparticles. DMG-PEG 2000 can be used for the preparation of liposomes for siRNA transfection, improving transfection efficiency.

DMG-PEG-NHS, MW 2000, is a compound composed of myristic acid and PEG linked by an amide bond, with NHS as an active ester group attached to the end of the PEG chain. It is utilized in applications such as protein/biomolecule modification, gene delivery, and biosensor development.

PEG2000-C-DMG is a PEGylated lipid that can be used in the preparation of Onpattro. Onpattro is a liver-targeted investigational RNAi therapeutic agent that targets the 3′ untranslated region of transthyretin mRNA, thereby reducing the production of both mutant and wild-type transthyretin.

DMG-PEG-Mal (MW 2000) is a PEG lipid that enhances the delivery efficiency and tissue specificity of poorly soluble drugs. It is applicable in drug delivery research.

m-PEG-DMG (MW 2000) is a PEG lipid utilized in the preparation of liposomes, which can be applied in drug delivery research.

DMG-PEG-SH (MW 2000) is a PEG derivative used for constructing drug delivery carriers.

PEG (2000)-C-DMG is a polyethylene glycolated derivative of 1,2-Dimyristoyl-sn-glycerol and can be combined with other lipids to form lipid nanoparticles (LNP) for siRNA delivery.

DMG-PEG-OH (MW 2000) is a polyPEG lipid that may be used for liposome or lipid nanoparticle (LNP) preparation for RNA drug delivery. DMG-PEG-OH (MW 2000) is employed in nucleic acid delivery research, particularly in lipid nanoparticle formulation studies, pharmacokinetic optimization of RNA carriers, and investigations of aqueous solubility modulation through polyethylene glycol chain incorporation.

DMG-PEG-Mal (MW 2000) is a PEG derivative composed of N,N-Dimethylglycine (DMG), PEG segments, and Maleimide. The Maleimide group reacts with thiols (-SH) to create stable thioether bonds. DMG-PEG-Mal (MW 1000) is applicable for drug delivery.