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Results for "
dg-70
" in TargetMol Product Catalog- Inhibitors & Agonists1
GSK1733953A
DG70
T27453930470-97-6
GSK1733953A can be used as a small molecule Mycobacterium tuberculosis respiration inhibitor with an inhibitory effect on MenG activity and an IC50 value of 2.6 ± 0.6 μM.GSK1733953A is a selective biphenylbenzamide with an inhibitory effect on the catalytic methylation of the Mycobacterium tuberculosis desmethylnaphthoquinone methyltransferase, and the MIC of GSK1733953A against Mycobacterium tuberculosis H4Rv was 8.37 μg ml. MIC of 8.37 μg ml and MIC of 1.2 to 9.6 μg ml against drug-resistant strains.GSK1733953A is a candidate compound for the treatment of tuberculosis.
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