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By Target- Androgen Receptor
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By Target By ResearchField- Cancer(1)
- Immune System(1)
- Inflammation(1)
By Natures- Ailanthus(1)
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Results for "
delta13-dehydrochaparrinone
" in TargetMol Product Catalog.- Inhibitors & Agonists1
- Natural Products1
- AilanthoneΔ13-DehydrochaparrinoneTQ0209981-15-7Ailanthone (AIL) is a natural compound derived from the tree Ailanthus altissima and has anti-hepatocellular carcinoma (HCC) properties. It can induce G0/G1 phase cell cycle arrest by downregulating the expression of cyclins and CDKs, while upregulating the expression of p21 and p27. Additionally, Ailanthone is a potent androgen receptor (AR) inhibitor, capable of inhibiting both the full-length androgen receptor (IC50: 69 nM) and constitutively active splice variants (IC50: 309 nM).
- $36
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