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(2)
By Target- DNA Methyltransferase
- Apoptosis(1)
- Nucleoside Antimetabolite/Analog(1)
- Pyroptosis(1)
- Others(1)
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Results for "
decitabine
" in TargetMol Product Catalog- Inhibitors & Agonists4
Decitabine
NSC 127716, Dacogen, 5-Aza-CdR, 5-Aza-2'-deoxycytidine
T15082353-33-5
Decitabine (Deoxycytidine) is a deoxycytidine analog, a DNA methyltransferase inhibitor with oral activity. Decitabine has antitumor activity and antimetabolic activity. Decitabine induces cell cycle arrest and apoptosis.
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Guadecitabine sodium
SGI-110 sodium, S-110 sodium
T12790929904-85-8
Guadecitabine sodium is a inhibitor of second-generation DNA methyltransferases (DNMT) .
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Guadecitabine
SGI-110
T16876929901-49-5
Guadecitabine is a second-generation DNA methyltransferases inhibitor. It is used for research on acute myeloid leukemia and myelodysplastic syndromes.
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Caspase-3 activator 1
T79743
Caspase-3 activator 1 (compound 4b), a Ru(III) metal complex, effectively inhibits gastric tumor growth and metastasis by mediating caspase-3 cleavage, enabling Caspase-3 to process gasdermin E (GSDME), resulting in GSDME-N terminus production and perforation of the gastric tumor cell membrane. Furthermore, compound 4b induces pyroptosis and subsequent immune responses and can be incorporated with decitabine (DCT) into the 4b-DCT-Lip lipid delivery system [1].
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