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Results for "
dc-34
" in TargetMol Product Catalog- Inhibitors & Agonists2
CCL-34
T211634943316-60-7
CCL-34 is an activator of Toll-like receptor 4 (TLR4). It significantly induces the expression of CD83 on dendritic cells (DC) and the production of IL-12p70 in a dose-dependent manner, thereby promoting DC maturation. CCL-34 enhances the allostimulatory activity of DC on the proliferation of naive CD4+CD45+RA+ T cells and their secretion of IFN-γ. Furthermore, CCL-34 can enhance antigen presentation capability in mice inoculated with doxorubicin-treated colorectal cancer cells. CCL-34 is applicable for research in immune stimulation.
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