dbco-peg5-dbco

DBCO-PEG5-DBCO is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules, enabling selective protein degradation through the ubiquitin-proteasome system within cells.

DBCO-NHCO-PEG5-NHS ester is a polyethylene glycol (PEG)-based linker used in the synthesis of PROTACs [1].

DBCO-PEG5-NHS ester is a PROTAC linker belonging to the PEG and Alkyl/ether classes for the synthesis of a range of PROTAC molecules.

DOTA-PEG5-C4-DBCO is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

DBCO-Amide-PEG5-acid is a non-cleavable ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs)[1].

Fmoc-N-amido-PEG5-azide is a PROTAC linker of the PEG class, used in the synthesis of PROTAC molecules. This compound functions as a click chemistry reagent due to its azide group, enabling copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with molecules containing alkyne groups. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition reactions (SPAAC) with molecules that have DBCO or BCN groups.

CG-PEG5-azido is a PROTAC linker classified under the PEG category, instrumental in synthesizing PROTAC molecules. This compound acts as a click chemistry reagent, incorporating an Azide group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) with Alkyne-containing molecules. Additionally, it can undergo strain-promoted azide-alkyne cycloaddition (SPAAC) with molecules bearing DBCO or BCN groups.