dbco peg10 dbco

DBCO-PEG10-DBCO is a PEG-based linker used in PROTACs, joining two essential ligands needed to form PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Azido-PEG10-amine is a non-cleavable ADC linker and PEG-based PROTAC linker that can be used to synthesise antibody-drug conjugates (ADCs) and PROTACs. It can undergo click chemistry reactions with molecules containing alkyne, DBCO or BCN groups.

LG-PEG10-click-DBCO-Oleic is a polyethylene glycol (PEG) derivative used as a linker in the synthesis of Proteolysis Targeting Chimeras (PROTACs)[1].

Azido-PEG10-CH2CO2-NHS is a PROTAC linker of the PEG class, utilized for synthesizing PROTAC molecules. It serves as a click chemistry reagent, featuring an Azide group that participates in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with alkyne-containing molecules. Additionally, it can engage in strain-promoted azide-alkyne cycloaddition reactions (SPAAC) with molecules that have DBCO or BCN groups.

Azido-PEG10-CH2COOH is a PROTAC linker belonging to the PEG category, useful for synthesizing PROTAC molecules. This compound is a click chemistry reagent containing an azide group, allowing it to participate in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with alkyne-containing molecules. Additionally, it can engage in strain-promoted alkyne-azide cycloaddition reactions (SPAAC) with molecules containing DBCO or BCN groups.

Azido-PEG10-propargyl is a PROTAC linker belonging to the PEG class, suitable for synthesizing PROTAC molecules. It features an azide group, enabling copper-catalyzed azide-alkyne cycloaddition reaction (CuAAC) with molecules containing alkyne groups. Additionally, it can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules that have DBCO or BCN groups.

Azido-PEG10-azide is a PROTAC linker belonging to the PEG category, utilized in the synthesis of PROTAC molecules. As a click chemistry reagent, it features azide groups capable of participating in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with alkyne-containing molecules. Additionally, it engages in strain-promoted azide-alkyne cycloaddition reactions (SPAAC) with DBCO or BCN-containing molecules.